There’s been a rumor floating around that Werewolves will have a role in Skyrim. Oblivion had vampires so why not werewolves in Skyrim? It is unclear if your character can become a werewolf or if you will encounter a group of them in the game, but we should know for sure on the 11th of November.
Another rumor making the rounds is cannibalism. Straight from the BBFC (which is the British version of the ESRB), they point out that a choice can be made within the game to eat human flesh. This doesn’t necessarily mean that cannibalism will take a large role within the world of Skyrim but it could still mean that it will have some part in the game, even if it is optional.