Transformers Prime started out as a cartoon for The Hub back in November of 2010, however it wasn’t until February of 2011 that the series actually started. It his controlled by Hasbro and has slightly darker themes than your normal cartoon.
Said cartoon is based in Nevada with three humans: Jack, Miko, and Rafaelalong. They are joined by five Autobots: Optimus, Bumblebee, Ratchet, Bulkhead and Arcee. As far as the Decepticon’s side, you have the usual Starscream and Megatron, along with new characters like Breakdown and Skyquake, to name a few.
The show’s universe is the same as High Moon‘s Transformers: The War for Cybertron, which means Activision‘s new game based off of the show is set in the same universe as well.